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Pancreatic Cancer Drug Offers Six More Months — episode cover art
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四十年拿不下来的靶点被拿下了。胰腺癌病人多活半年,代价是一个月三万九千八百美元。

Pancreatic Cancer Drug Offers Six More Months

About this story

Pancreatic Cancer Drug Offers Six More Months. HSK 3 Chinese listening practice.

This is an HSK 3-4 Chinese listening episode that runs about 2 minutes. The full Mandarin script is shown with tap-for-pinyin and a line-by-line English translation, so you can listen and read at once — comprehensible input in the sense of Stephen Krashen's i+1 theory. It teaches 6 key vocabulary words such as 消息、机会、放弃 and walks through 3 grammar patterns, each explained in English with examples. The same news story is retold at 4 difficulty levels — use the level selector above to find the version that is challenging but still understandable for you.

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原文

Read the complete story in Chinese. Reveal pinyin and English only when you need them.

上个星期,美国批准了一种治胰腺癌的新药。
胰腺癌是最难治的癌症之一,几十年来,几乎没有好消息。
以前,确诊之后的中位生存期,不到七个月。
中位的意思是,一半的人活不过这个时间。
新药出来以后,这个数字,变成了十三个月。
多出来的,是半年。
再说这个药难在哪里。
人身上有一种蛋白,管着细胞长不长。
它一旦坏掉,就会让细胞,一直长下去。
在胰腺癌里,超过九成的病人,坏的都是这一种蛋白。
科学家早就知道,按住它就有机会。
问题是,按不住。
它表面太光滑,药抓不住。
所以医学界给它起了一个外号,叫不能成药的靶点。
现在,有人把它按住了。
而且它不是打针,是一天一片的药片,在家吃就行。
副作用也有,而且不小。
超过八成六的病人,身上会长皮疹。
但真正值得比的,是病人能不能坚持。
化疗太重,很多人中途就放弃了。
吃这个药的人,中途停药的明显更少,也没那么疼。
到这里为止,这是几十年里最好的一条新闻。
然后是价格。
一个月的药,三万九千八百美元。
一个月,不是一年。
药摆在那里,能不能吃到,是另一个问题。
你想一想:
一种药救得了人,但很多人买不起,它算不算一个好消息?
English transcript reference

Last week, America approved a new drug for pancreatic cancer.

Pancreatic cancer is one of the hardest cancers to treat. For decades there has been almost no good news.

Before this, median survival after diagnosis was under seven months.

Median means half of all patients do not live past that point.

With the new drug, that number becomes thirteen months.

The difference is half a year.

Now, why this drug was so hard to make.

There is a protein in the body that governs whether cells keep growing.

Once it breaks, it makes cells go on growing without stopping.

In pancreatic cancer, over ninety percent of patients have this same broken protein.

Scientists knew long ago that if you could pin it down, you had a chance.

The problem was that you could not pin it down.

Its surface is too smooth. A drug gets no grip.

So the medical world gave it a nickname: the undruggable target.

Now someone has pinned it down.

And it is not an injection. It is one tablet a day, taken at home.

There are side effects, and they are not minor.

More than eighty-six percent of patients get a skin rash.

But what is really worth comparing is whether patients can keep going.

Chemotherapy is so heavy that many people give up partway.

On this drug, far fewer people stop treatment, and they are in less pain.

Up to this point, it is the best piece of news in decades.

Then comes the price.

One month of the drug: thirty-nine thousand eight hundred dollars.

One month, not one year.

The drug is sitting there. Whether you can get it is a separate question.

Think about it:

If a drug can save people but many cannot afford it, does it count as good news?

Listen again

Try it without the transcript and notice what sounds clearer.

What vocabulary does this episode teach?

词汇
xiāoxinews, a piece of news

几十年来,几乎没有好消息 — for decades, almost no good news.

jīhuìchance, opportunity

按住它就有机会 — pin it down and you have a chance.

fàngqìto give up

很多人中途就放弃了 — many people give up partway.

míngxiǎnobvious, markedly

中途停药的明显更少 — markedly fewer stop the drug partway.

bǎdiǎndrug target

不能成药的靶点 — the undruggable target. 靶 is the bullseye on a target.

fùzuòyòngside effect

副 means secondary; 作用 means effect.

* beyond level超纲词

What grammar patterns appear in this episode?

语法

一旦……,就……

Once A happens, B follows. More formal than 如果.

它一旦坏掉,就会让细胞一直长下去。 — Once it breaks, it makes cells keep growing.

值得 + verb

Worth doing.

但真正值得比的,是病人能不能坚持。 — What is really worth comparing is whether patients can keep going.

到这里为止

"Up to this point" — marks a boundary before a turn.

到这里为止,这是几十年里最好的一条新闻。 — Up to this point, it is the best news in decades.

Proper nouns

专有名词
美国Měiguóthe United States

Sources

来源

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