A Chinese podcast · Same story, 4 levels

四十年拿不下来的靶点被拿下了。胰腺癌病人多活半年,代价是一个月三万九千八百美元。
A Target Called Undruggable for Forty Years Just Fell. Pancreatic Cancer Patients Gain Six Months, at $39,800 a Month.
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A Target Called Undruggable for Forty Years Just Fell. Pancreatic Cancer Patients Gain Six Months, at $39,800 a Month. HSK 3 Chinese listening practice.
This is an HSK 3-4 Chinese listening episode that runs about 2 minutes. The full Mandarin script is shown with tap-for-pinyin and a line-by-line English translation, so you can listen and read at once — comprehensible input in the sense of Stephen Krashen's i+1 theory. It teaches 6 key vocabulary words such as 消息、机会、放弃 and walks through 3 grammar patterns, each explained in English with examples. The same news story is retold at 4 difficulty levels — use the level selector above to find the version that is challenging but still understandable for you.
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原文Read the complete story in Chinese. Reveal pinyin and English only when you need them.
English transcript reference
Last week, America approved a new drug for pancreatic cancer.
Pancreatic cancer is one of the hardest cancers to treat. For decades there has been almost no good news.
Before this, median survival after diagnosis was under seven months.
Median means half of all patients do not live past that point.
With the new drug, that number becomes thirteen months.
The difference is half a year.
Now, why this drug was so hard to make.
There is a protein in the body that governs whether cells keep growing.
Once it breaks, it makes cells go on growing without stopping.
In pancreatic cancer, over ninety percent of patients have this same broken protein.
Scientists knew long ago that if you could pin it down, you had a chance.
The problem was that you could not pin it down.
Its surface is too smooth. A drug gets no grip.
So the medical world gave it a nickname: the undruggable target.
Now someone has pinned it down.
And it is not an injection. It is one tablet a day, taken at home.
There are side effects, and they are not minor.
More than eighty-six percent of patients get a skin rash.
But what is really worth comparing is whether patients can keep going.
Chemotherapy is so heavy that many people give up partway.
On this drug, far fewer people stop treatment, and they are in less pain.
Up to this point, it is the best piece of news in decades.
Then comes the price.
One month of the drug: thirty-nine thousand eight hundred dollars.
One month, not one year.
The drug is sitting there. Whether you can get it is a separate question.
Think about it:
If a drug can save people but many cannot afford it, does it count as good news?
Listen again
Try it without the transcript and notice what sounds clearer.
What vocabulary does this episode teach?
词汇几十年来,几乎没有好消息 — for decades, almost no good news.
按住它就有机会 — pin it down and you have a chance.
很多人中途就放弃了 — many people give up partway.
中途停药的明显更少 — markedly fewer stop the drug partway.
不能成药的靶点 — the undruggable target. 靶 is the bullseye on a target.
副 means secondary; 作用 means effect.
* beyond level超纲词
What grammar patterns appear in this episode?
语法一旦……,就……
Once A happens, B follows. More formal than 如果.
它一旦坏掉,就会让细胞一直长下去。 — Once it breaks, it makes cells keep growing.
值得 + verb
Worth doing.
但真正值得比的,是病人能不能坚持。 — What is really worth comparing is whether patients can keep going.
到这里为止
"Up to this point" — marks a boundary before a turn.
到这里为止,这是几十年里最好的一条新闻。 — Up to this point, it is the best news in decades.
Proper Nouns
专有名词Sources
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